Our study systematically evaluated the molecular biological characteristics and prognostic value of PR genes/lncRNAs in BLCA and identified an eight-PR-lncRNA signature (including AC021321.1, LINC00426, STAG3L5P-PVRIG2P-PILRB, SNHG16, NR2F2-AS1, AC068196.1, RBMS3-AS3 and AC104825.1) related to the prognosis of BLCA patients. The gene discussed is PILRB; the disease is bladder transitional cell carcinoma.