We found that ELANE, IL6, NLRP1 and NLRP3 had a low differential expression in BLCA; however, AIM2, CASP3, CASP5, CASP6, CASP8, GPX4, GSDMB, GSDMD, NLRP2, NLRP7, PLCG1 and PYCARD had a high differential expression in BLCA (Figure 1A). The gene discussed is GSDMD; the disease is bladder transitional cell carcinoma.