The ESTIMATE assessment of the TIME in STAD also revealed that the immune cell score (Figures 5A,C) and tumour stroma score (Figures 5A,D) were significantly higher in the high CHSY3 expression group than in the low CHSY3 expression group, while the tumour purity score (Figures 5A,E) demonstrated the opposite phenomenon. This evidence concerns the gene CHSY3 and neoplasm.