Published meta-analyses with largest sample size were performed in 2013 to detect the relationship of TP53 codon 72 (59 studies including 29,801 cases and 35,436 controls) and IVS3 16 bp (19 studies including 4,479 cases and 4,683 controls), and in 2011 for IVS6+62A > G (14 studies including 8,787 cases and 9,869 controls) with BC risk (He et al., 2011; Dahabreh et al., 2013; Wu et al., 2013). Here, TP53 is linked to breast cancer.