It can be seen from Figure 3B that the KEGG pathway enrichment analysis showed that the target DE-mRNAs were significantly enriched in pathways involved in EGFR-TKI resistance of NSCLC, such as the PI3K/Akt pathway, MAPK signaling pathway, cell cycle, and apoptosis. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.