Syndromes with epilepsy are caused by ADNP, ARID1A, CASR, CHD7, COL3A1, DGUOK, KCNK4, KMT2A, KMT2C, MECP2, NIPBL, PIGO, SETBP1 and UBE3A et al. (Supplementary Table S1). The gene discussed is SETBP1; the disease is epilepsy.