In addition, conforming with our bioinformatics analysis, previous research found that NRP1 might modulate EMT to not only contribute to the growth and metastasis of tumors (Chen et al., 2018; Ma et al., 2019; Ding et al., 2020), but also induce drug-resistance and radiation resistance in cancers (Abdullah et al., 2021; Cong et al., 2021). The gene discussed is NRP1; the disease is cancer.