CD4 and Opportunistic infection: The univariate regression analysis results showed that older age ≥50 years (OR = 8.36, 95% CI: 3.01–23.22, p = 0.001), chronic co-morbidities (OR = 4.70, 95% CI: 1.42–15.58, p = 0.011), opportunistic infections (OR = 23.05, 95% CI: 5.93-89.57, p = 0.001), and CD4 count <100/μl (OR = 0.19, 95% CI: 0.05–0.76, p = 0.019) were associated with increased odds of SARS-CoV-2 infection among PLWH.