In addition, both CXCL13 and CD163 were inversely associated with IDH1 mutations (CXCL13, p = 0.0007; CD163, p = 0.0315, Table 2), implying that fewer M2 TAMs were present in IDH-mutant astrocytomas compared to wild-type. This evidence concerns the gene IDH1 and astrocytoma (excluding glioblastoma).