According to the results of the multivariate analysis, we settled classes of WHO grade I meningioma that achieved GTR using three clinical/histopathological/genomic factors as follows: “Good”: Ki-67 index < 4 and non-NF2 meningioma, Ki-67 index < 4 and “Infratentorial NF2”; Intermediate: MIB-1 index ≥ 4 or “Supratentorial NF2”; Poor: Ki-67 index ≥ 4 and “Supratentorial NF2” (Fig. 5). This evidence concerns the gene NF2 and meningioma.