However, when ITGB1 and KLF14 constructs were co transfected, the above effect was reversed, and the apoptosis rate of cervical cancer cells overexpressing both ITGB1 and KLF14 (Lv-ITGB1 + Lv-KLF14) was higher than that of the Lv-control (KLF14) + Lv-ITGB1 group. The gene discussed is KLF14; the disease is cervical carcinoma.