Increased LDL retention and accelerated atherosclerosis were reported in a progerin‐induced atherosclerosis murine model with either ubiquitous or VSMC‐specific progerin overexpression, suggesting a close relationship between atherosclerosis and LDL‐induced VSMC senescence (Hamczyk et al., 2018b). The gene discussed is LMNA; the disease is atherosclerosis.