Focusing on the UM-SCC47 cells, we find that RON and ABL1 are active in the tumor cells, as evidenced by phosphorylation of Y1238/1239 and Y412 in their respective kinase domains, as well as Y245 in the SH2-kinase linker of ABL1 (29, 41) (Fig. 3D). This evidence concerns the gene MST1R and neoplasm.