Sweeney et al. [47] showed that the diagnostic power of a set of three genes (GBP5, DUSP3, and KLF2) to separate active TB from HCs with AUC of 0.90, sensitivity of 0.85 and specificity of 0.93, latent tuberculosis with AUC of 0.88, sensitivity of 0.80 and specificity of 0.86, and other diseases with AUC of 0.84, sensitivity of 0.81 and specificity of 0.74 in eight independent datasets composed of both children and adults. The gene discussed is GBP5; the disease is tuberculosis.