Importantly, we demonstrated that ANLN expression was positively correlated with cancer-associated fibroblasts in BLCA, BRCA-LumA, ESCA, HNSC, human papillomavirus-negative HNSC, KIRC, KIRP, LUAD, MESO, SKCM, metastatic SKCM, THCA, and USC, but negatively correlated with BRCA and TCGT (Fig. 7A and B). Here, ANLN is linked to cancer.