For premenopausal women (N = 1157), current smoking, breastfeeding history, CHC use, CRP level, history of osteoporosis, osteoarthritis, salpingectomy, endometriosis, fibroids, CAD, and non-ovarian cancer demonstrated possible associations with CA125 concentration (p < 0.25) via linear regression models (Table 3). The gene discussed is CRP; the disease is osteoporosis.