For postmenopausal women, Akinwunmi et al. had demonstrated that both osteoporosis and osteoarthritis were associated with lower levels of CA125, [9] however our study did not reveal such significant associations (N = 76 for osteoporosis and N = 225 for osteoarthritis in Akinwunmi’s study, versus N = 203 for osteoporosis and N = 175 for osteoarthritis in this study). Here, MUC16 is linked to osteoporosis.