History of breastfeeding in postmenopausal women (N = 561) was more likely to be associated with CA125 level ≥ 35 U/ml (OR = 2.46, 95% CI [1.12, 5.41] p = 0.026), as was history of CAD (N = 58) (OR = 5.00, 95% CI [1.45, 17.17], p = 0.011). The gene discussed is MUC16; the disease is coronary artery disorder.