It is worth mentioning that the gene group, AR-KLK3-AZGP1-(STRING network, Fig. 4), was mentioned in a patent application as biomarkers for PCa diagnosis in 2015 [54], and were also detected in proteomic studies of seminal plasma [45], suggesting that there is a strong androgen-dependent association among these genes. This evidence concerns the gene KLK3 and posterior cortical atrophy.