Carrick Therapeutics announced it was granted Fast Track designation for the CDK7 inhibitor CT7001 in combination with chemotherapy for the treatment of locally advanced or metastatic TNBC, while Syros Pharmaceuticals announced it will begin clinical investigation of the CDK7 inhibitor SY-5609 in combination with chemotherapy in pancreatic cancer [89]. The gene discussed is CDK7; the disease is pancreatic neoplasm.