To identify genes with prognostic value in GC, we performed transcriptome sequencing on the tumour and adjacent tissues of patients with GC and combined it with the GEO database (five datasets GSE14210, GSE15459, GSE22377, GSE29272 and GSE51105 are combined, total number of cases = 592) for survival analysis to screen out the downregulated LHPP gene (Fig. 1A and Supplementary Fig. 1, 2). Here, LHPP is linked to gastric cancer.