The liver cirrhosis polygenic score was not associated with diagnosis of liver cirrhosis in p.C282Y homozygotes (p > 0.05), though the association was significant in the larger HFE wild‐type group (ORmales, 1.20: 95% CI, 1.16–1.23; p = 6 × 10−38). The gene discussed is HFE; the disease is cirrhosis of liver.