Indeed, stratifying FTD patients based on whether they had 0, 1 or 2 copies of the risk SNPs in UNC13A showed a strong association between the number of risk SNPs and a reduction in patient survival time after disease onset (patients with one copy of the risk SNPs live shorter than those with zero and those with two copies of the risk SNPs live even shorter),10 consistent with previous analyses indicating decreased survival in ALS and FTD patients harbouring UNC13A variants.25, 26, 27, 28. This evidence concerns the gene UNC13A and amyotrophic lateral sclerosis.