The tear film concentrations of VEGF and IL-10 were found to be significantly increased, whereas TNF-α, IL-1β, IL-8, and GM-CSF were significantly lower among the COVID-19 patients admitted to the hospital than among the SARS-CoV-2-negative controls (Figure 1, Supplementary Figure S1 and Table 3). Here, CSF2 is linked to COVID-19.