They showed that a high preoperative NLR and a low preoperative albumin level were independent risk factors for a reduced lumbar SMI value in patients with CRC (NLR, OR 1.78, 95% CI 1.29–2.45, p < 0.001; albumin, OR 1.8, 95% CI 1.17–2.74, p = 0.007). The gene discussed is ALB; the disease is colorectal carcinoma.