ABCB5 and cystic kidney disease: To conclude, our study provides a wide description of the gene profile outcomes obtained by treating PKD/Mhm (Cy/+) rats with ABCB5+ or ASC cells and derived conditioned media, suggesting that ABCB5+ or ASC cell administration, and ABCB5+-derived CoCM+ and ASC-derived CM treatments might be efficient alternative therapies for cystic kidney disease.