As already reported by the GFM study, thrombocytopenia was associated with Hb values >12 g/dL in 13% of the subjects in our cohort, and in 7% of cases it represents the only cytopenia at diagnosis; these patients were all males and with marrow blasts <5%, thus raising the need of a careful differential diagnosis with idiopathic thrombocytopenic purpura (ITP). This evidence concerns the gene GSTM1 and thrombocytopenic purpura.