We also evaluated the activity of SOD and the concentration of Cu and Zn in the subgroups of women with PCOS, dividing them according to occurrence of insulin resistance (HOMA-IR ≥ 2.0) and insulin sensitivity (HOMA-IR < 2.0), as well as their weight, normal weight (BMI < 25.0) and overweight (BMI ≥ 25.0). The gene discussed is INS; the disease is Insulin resistance.