In a study by Hachisu et al. in patients with AE of IPF, high CRP (hazard ratio (HR) 1.080; 95% CI 1.022–1.141; p = 0.006), LDH (HR 1.003; 95% CI 1.000–1.006; p = 0.037) and low total cholesterol levels (HR 0.985; 95% CI 0.972–0.997; p = 0.018) were associated with in-hospital mortality [28]. Here, CRP is linked to idiopathic pulmonary fibrosis.