We can assume that after exclusion of other causes such as acute coronary syndrome, tachyarrhythmia, hypertensive crisis, and acute heart failure, elevation in high sensitivity troponin in the clinical context of viral infection and in patients with chest pain, is highly suggestive for acute myocarditis Moreover, our results support the prognostic value of NT-proBNP in patients with chest pain and elevated troponin regardless of the final diagnosis. This evidence concerns the gene NPPB and myocarditis.