TNF and vasculitis: Furthermore, other researchers have demonstrated that treatment with a neutralizing Ab against moesin drives the release of IFN–γ, TNF–α, and IL–6 from several immune cells derived from human peripheral whole blood [50,51], and that serum concentrations of IFN–γ, TNF–α, and IL–6 were higher in patients with myeloperoxidase–antineutrophil cytoplasmic Ab-associated vasculitis, who are positive for anti-moesin Ab than in those negative for anti-moesin Ab [51].