PLAU and breast carcinoma: The role of the other elements involved in the blood clot liquefaction process is poorly understood, although Look et al. showed that tissue plasminogen activator (t-PA) and urokinase plasminogen activator (u-PA) [17], and Ruszkowska-Ciastek et al. [18] demonstrated that t-PA, might also be prognostic indicators in breast cancer.