Resistance to an apoptotic cell death was demonstrated in CD133+ GBSCs isolated from patients with glioblastoma compared to CD133, non-CSC fractions by raised confrontation to various chemotherapeutical agents, which was related with increased expression of various anti-apoptotic mRNAs, including BCL-XL, BCL-2, IAPs, and FLIP [28]. Here, PROM1 is linked to glioblastoma.