The expression of YAP and TAZ proteins was significantly decreased in colon cancer cell HCT116 (p < 0.01), and the expression of YAP and TAZ proteins was also significantly decreased in colon cancer cell LOVO (p < 0.01), indicating that DTB can indeed inhibit the elevation of YAP and TAZ, possibly by decreasing the association of YAP and TAZ with transcription factors in the nucleus or crosstalk with the cellular mitochondrial apoptosis pathway, thereby inducing apoptosis of colon cancer cells (Figure 12 and Figure 13). Here, TAFAZZIN is linked to malignant colon neoplasm.