YAP/TAZ is amplified and preferentially localized in the nuclei of several tumors: the lung, pancreas, esophagus, stomach, skin, colon, prostate cancer, liver cancer, ovarian cancer and breast cancer medulloblastoma, glioma, and oral squamous cell carcinoma [29,30,31]. The gene discussed is TAFAZZIN; the disease is Familial prostate cancer.