RDH8 and retinal degeneration: It was observed that the intraperitoneal injection of quercetin or myricetin at 20 mg/kg for ATP-binding cassette subfamily member 4 (Abca4−/−) retinol dehydrogenase 8 (Rdh8−/−) mice 30 min before exposure to 10,000 Lux light for 45 min showed a protective effect against light-induced retinal degeneration by maintaining retinal morphology and function [39].