Experimental knockdown of miR-98-5p by injection of an adeno-associated virus-anti-miR-98-5p into the hippocampi of AD model mice restored α7 nAChR protein levels and attenuated Aβ pathology, synaptic dysfunction, cognitive decline, and neuroinflammation [80] (Table 2). The gene discussed is CHRNA7; the disease is Alzheimer disease.