CAT and inflammatory bowel disease: However, when LYCO was administered 3 days before IBD, it remarkably (p < 0.01, n = 6) increased the mean catalase colonic tissue activity on days 2 and 7 of IBD, from 2.34 ± 0.32 (no LYCO) to 5.72 ± 0.9 and from 3.17 ± 0.36 to 5.41 ± 0.48 nmol/min/mg tissue, respectively.