However, LYCO given after IBD produced a significant (p < 0.01, 0.001, n = 6) reduction in IL-1β levels from 301.30 ± 46.11 (no LYCO) to 34.20 ± 6.18 and from 140.78 ± 34.86 (no LYCO) to 40.38 ± 4.47 ng/mg of protein on days 2 and 4 days of IBD, respectively. This evidence concerns the gene IL1B and inflammatory bowel disease.