Additionally, the mRNA expression of five ovarian development-related genes (FOXL2, GDF9, LIF, OCT4, and SCF) were measured; FOXL2, OCT4, GDF9, and LIF were significantly downregulated (Figure 4E–H), whereas that of SCF was significantly upregulated in the CTX group compared with the control group (Figure 4I). Here, FOXL2 is linked to cerebrotendinous xanthomatosis.