PGR and endometrium adenocarcinoma: When human endometrial adenocarcinoma ishikawa cells were treated with resveratrol as a single agent, the estrogen-inducible progesterone receptor was not increased, and progesterone receptor expression induced by treatment with 17beta-estradiol (E(2)) was inhibited by resveratrol in a dose-dependent manner at both the protein and mRNA levels [115].