Nevertheless, Schmidkonz et al. have recently demonstrated the high performance of [99mTc]Tc-MIP-1404 also for the detection of PSMA-positive lesions in patients who presented biochemical recurrence of PCa with low (from 0.5 to 1 ng/mL) and very low (0.2 and 0.5 ng/mL) serum PSA levels. This evidence concerns the gene KLK3 and posterior cortical atrophy.