NLRP3 and Hypoglycemia: One of the ketone bodies, 3-hydroxybutyric acid, blocks NLR family pyrin domain containing 3 (NLRP3) inflammasome and attenuates caspase-1 and interleukin-1β secretion in mouse models and is believed to reduce hypoglycemia-related neuronal apoptosis, increase the number of motor neurons, increase neuronal activity and angiogenesis, and protect neuronal cell cultures from the development of amyloid pathology [8,9,10].