In this contest, Franzago et al. showed an increased risk of GDM in women carriers of the TT genotype of the TCF7L2 rs7903146 [177,178], as well as an association between nutrigenetic variants in PPARG2, APOA5, MC4R, LDLR, and FTO genes and lipid parameters at the third trimester of pregnancy. The gene discussed is TCF7L2; the disease is gestational diabetes.