Within the IBS patients at baseline, age correlated inversely with visfatin (rs = (−0.216), p = 0.038) and weight inversely with visfatin (rs = (−0.228), p = 0.032) and total ghrelin (rs = (−0.310, p = 0.003), whereas age correlated positively with enkephalin (rs = 255, p = 0.013), and weight correlated positively with PAI-1 (rs = 0.348, p = 0.001). Here, GHRL is linked to irritable bowel syndrome.