In contrast, hybrid grouper fed soybean meal or fermented soybean meal for 10 days developed enteritis and showed an increase in the expression of pro-inflammatory genes (IL-1β, IL-8, IL-17, and TNFα), as well as a decrease in anti-inflammatory genes (IL-4, IL-10, and transforming growth factor β1—TGFβ1) and immune parameters, such as lysozyme, complement factors C3 and C4, and IgM [134]. This evidence concerns the gene CXCL8 and enteritis.