HLA-C and cancer: Advanced in silico models are being developed that estimate several characteristics, such as MHC bind capacity [171], T-cell receptor recognition [172], immunogenicity [173], subcellular location [174,175], etc. The implementation of these tools in machine learning models that unify estimates for several features is paramount to develop integrated computational pipelines to profile and characterize classical and new vaccination targets for T. gondii, similar to the approach recently applied in cancer derived neoantigens [176].