Clinical studies with ensartinib have been conducted to determine the pharmacokinetics of ensartinib (ClinicalTrials.gov Identifiers: NCT03804541, NCT03510611, NCT03536481, NCT03608007) and its efficacy in patients with ALK-positive NSCLC (NCT02959619, NCT04415320, NCT03753685, NCT02767804, NCT04146571, NCT03215693, NCT03737994), patients with melanoma (NCT03420508), and patients with relapsed or refractory advanced solid tumors, non-Hodgkin lymphoma or histiocytic disorders (NCT03213652, NCT03155620). The gene discussed is ALK; the disease is non-small cell lung carcinoma.