CRP and alcohol abuse: In HPV- patients, higher pre-treatment CRP (HR = 3.45; 95% CI: 1.37–8.68; p = 0.008), NRS 2002 (HR = 3.83; 95% CI: 1.22–12.01; p = 0.021), and alcohol abuse (HR = 6.39; 95% CI: 1.40–29.14; p = 0.017) were significant independent adverse prognostic factors, while female gender (HR = 0.12; 95% CI: 0.02–0.58; p = 0.009) was a good predictor for OS.