Second, GL261 LDH-A KD cells did not establish flank tumors in immune-competent C57BL/6 mice, whereas GL261 NC tumors formed after a 40-day growth delay, indicating that the metabolic rearrangements of GL261 LDH-A KD cells did not support s.c. tumor growth in immune-competent C57BL/6 mice. Here, LDHA is linked to neoplasm.