Since SCLC cell lines are classified into four biologically distinct subtypes (ASCL1, NEUROD1, YAP1, and POU2F3) [39], we selected DMS53, H146, H128, H372, DMS153, H69, H209 (ASCL1), H446 (NEUROD1), DMS114, H196 (YAP1), H1048, and H526 (POU2F3) in our study, representing each subtype. This evidence concerns the gene POU2F3 and small cell lung carcinoma.