CD8A and meningioma: Rapp et al. analyzed the presence of TILs in 97 newly diagnosed and 62 recurrent high-grade meningiomas, reporting that a higher number of cytotoxic TILs (CD3+ CD8+ FOXP3-) were associated with an improved PFS, while recurrent meningiomas were characterized by lower numbers of TILs and proportions of PD-1+CD8+ T cells [57].