In fact, the higher extent of association of liposomes targeting nucleolin relative to the non-targeted counterpart, evidenced by autoradiography in patient-derived tumor sections (Figure 3) and in lung cancer cell lines (by flow cytometry, Figure 5A), was likely due to cell surface expression of nucleolin, which further supported the original hypothesis that nucleolin qualifies as a therapeutic target in lung cancer. The gene discussed is NUCLEOLIN; the disease is neoplasm.