Herein, a cohort analysis of nucleolin mRNA expression in two TCGA datasets [29] (lung adenocarcinoma and squamous carcinoma) was performed in parallel with an immunochemical detection of the nucleolin levels in different histopathological subtypes of pulmonary carcinoma, surgically resected from patients, and in lung cancer cell lines. The gene discussed is NUCLEOLIN; the disease is squamous cell carcinoma.