EGFR and lung carcinoma: In 2011, the results of the mutational study of genes responsible for lung cancer (EGFR, KRAS, BRAF, HER2, AKT1, PIK3CA, MEK1, EML4-ALK, MET) were published, identifying the existence of at least one mutation in the above genes in more than 60% of the samples studied (Figure 2).