Correspondingly, CERS4 overexpression is significantly associated with lower risks of tumor progression or better prognostic outcome in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), head and neck squamous cell carcinoma (HNSC), KIRC, LUAD, and pancreatic adenocarcinoma (PAAD) as indicated by the blue bold outlines on the heatmap (Figure 3C). This evidence concerns the gene CERS4 and pancreatic adenocarcinoma.